Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Most microscopes can only illuminate objects down to a certain size before tiny features blur together. This blurring is known as the diffraction limit of light. Super-resolution imaging techniques, ...

Cryo-electron microscopy and single-molecule experiments show how phosphorylated M18BP1 relieves condensin II autoinhibition, enabling stable DNA binding and compaction in vitro.

In recent years, technologies that allow scientists to study a person's DNA at single-molecule resolution have vastly expanded our knowledge of the human genome, the microbiome, and the genetic basis ...

Gladstone Senior Investigator Vijay Ramani, PhD, (left) and collaborator Siva Kasinathan, MD, PhD, led a study that demonstrates how two new tools can perform single-cell genetic sequencing using less ...

Thymine suffers more UV damage than uracil in lab tests, but its damage pathways could help explain its place in DNA.

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...

DNA Shield provides offline storage for critical digital assets, data that must remain unchanged and protected from emerging ...

Schematic showing a single DNA duplex bridging two gold electrodes (yellow) patterned on a silicon nitride substrate (green). The setup allows measurement of electrical conductance as metal ions bind ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...